Showing posts with label Medical News Commentaries. Show all posts
Showing posts with label Medical News Commentaries. Show all posts

Monday, 27 April 2015

Nepal Needs Our Help




Credit: Krish Dulal
Image result for images for nepal earthquakeI will like to highlight the recent 7.8 magnitude earthquake in Nepal. I am quite sure you are aware of the details. I will not focus on the fact that presently over 3700 people are dead,7000 injured and millions of dollars worth of infrastructure destroyed. The death toll is rising by the minute.

Rather, my focus is on what we can do to help. Nepal needs relief materials, food, water, sanitation materials, medical assistance and a lot of other things. The country has just one major airport with one runway. Getting materials in has been a difficult task.

However, several organizations are already in Nepal and you can send your donations to them. I will list some of them below.

Please, lets be our brothers' keepers and send what we can. Click on the links below to go to the donation sites of the various organizations already in Nepal.

The Salvation Army: Click here

Mercy Corps: Click here

Handicap International: Click here

Doctors Without Borders: Click Here

American Jewish World Service: Click here

Oxfam: Click here

International Medical Corps: Click here

Red Cross: Click here

UNICEF: Click here

Save The Children: Click here

Canadian Medical Assistance Teams: Click here

World Vision: Click here

Catholic Relief Services: Click here

Thank you for your kindness.

My post on 'Using Checklists to reduce Medical Errors' will be coming up soon...

Tuesday, 21 April 2015

Did a ‘deity’ Actually Kill the ‘Ondo 18’?

Map of Nigeria showing Ondo State (see arrow)

Recently 18 Okada Riders (Commercial Motor Cyclists) died from a ‘mysterious’ illness in Irele, Ondo State, Southwest Nigeria. 5 others are in a hospital receiving treatment for the presently unknown disease. The locals claimed the dead men were killed by a deity. An in-depth analysis of the story will reveal 3 ‘deities’ that may have been responsible for their deaths.

‘deity’ #1- Malokun Shrine


The people of the community claimed that the 18 young men who died were punished for stealing sacred objects from the Malokun shrine. It is generally believed in Africa that mystic gods and goddesses can mete out punishment to criminals.  I really can’t prove this story so let’s move on to the next possible deity.
‘deity’ #2- Herbicide Poisoning
The initial hypothesis from the World Health Organization (WHO) was herbicide poisoning as the cause of death. This may be corroborated by the fact that the men all drank an herbal substance shortly before their deaths. Herbicide poisoning is actually quite lethal so this ‘deity’ may have had a hand in their death.

 Dr A.G Iyagbe, a Nigerian Scientist who studied herbicide use in South-South Nigeria in 2013 noted that many farmers who used herbicides bought them from the open market. His study also noted that the farmers did not use accurate measurements in preparing spray mixtures. In addition, they disposed left over spray mixture in local rivers and streams and had limited knowledge of the dangers of herbicide use.

Another Nigeria scientist, Dr. John Gushit in his 2012 Study noted the presence of herbicide residues in Fadama and Upland soils in North- Central Nigeria months after their use.

The unregulated availability, improper use and careless disposal of herbicides by farmers can lead to the contamination of crops and the environment. It is possible therefore that the 18 dead men somehow ingested an herbal mixture that was contaminated by herbicides. Toxicology may prove this.

 ‘deity’ #3- Methanol Poisoning

According to the Ondo State Government Spokesman this ‘deity’ likely caused the deaths of these 18 men and the illness of the remaining 5. The 23 men were said to have consumed a local brew known as Ogogoro. As is the practice with millions of Nigerians (even my Auto Mechanic is a consumer), Ogogoro is frequently mixed with roots and local herbs before consumption. There is a myth that this mixture treats malaria, makes people healthy and also ‘charges’ the brain. These men were alleged to have taken this Ogogoro-Herbs Mixture. Ogogoro is akin to Moonshine, an illicit brew made popular in America by the Appalachian distillers in the 1700s and 1800s.

Ogogoro also known as Sapele Water is a common Nigerian spirit made by distilling Raffia Palm wine. It contains 30-60% alcohol and is a source of income for many economically disadvantaged Nigerians who brew it in their homes. Sometimes, cheap methanol is added to increase the alcohol concentration of the drink.

However, it seems plausible that the methanol contaminant came from the roots and wood (local herbs) added to the mixture by the sellers. It is well known that methanol is the simplest alcohol which is produced by distilling wood. That is why it is also called wood alcohol.

Thursday, 2 April 2015

BUHARI and the Future of Healthcare in Nigeria




It is no longer news that Nigeria’s former Military Head of State (December 1983-August 1985), General Muhammadu Buhari (GMB) is now its President-Elect.  Since his historic victory on March 31st 2015, I have pondered over the future of the Nigerian health industry under a GMB and an All Progressive Congress (APC) presidency. Sometimes, to determine the future, one may have to look back at the past. Using GMB’s antecedents and the APC’s manifesto on health, one may deduce how the health sector will fare under him. Before I continue, I must state that I am not a member of any political party. I am simply a Nigerian Blogger and a concerned stakeholder in the Nigerian project.

So, what will a GMB presidency bring to the health sector? What is expected of GMB in the next 4 years?

Firstly, the foundation of a viable health sector in any country is a solid Primary Health Care System. In my opinion, without a functional primary care system, we will never get it right in the health sector as a nation. A good primary healthcare system is a necessary focal point for the prevention, early detection, treatment and monitoring of diseases. As the Petroleum Trust Fund (PTF) Executive Chairman (1994-1999), GMB helped build Primary Health Care Centers (PHCs) all over Nigeria. So, I think GMB will focus on the primary healthcare sector. He will most likely empower and adequately supervise the National Primary Healthcare Development Agency (NPHCDA) to ensure that it actually carries out its function. Increasing the life expectancy of Nigerians by an additional 10 years is one of the policies of the APC. A good primary health care system will help in achieving this dream.


In addition, a GMB presidency may educate and encourage patients to visit the primary health centers as their first contact with the nation’s health system. This will free personnel and facilities in tertiary centers to focus on research and treatment of more serious medical issues. With a strong primary health system, quacks and charlatans in our health sector will gradually be phased out. Rural dwellers will no longer visit quacks when they know that their local PHC is properly staffed, adequately equipped and stocked with affordable generic drugs.

In his first stint as Head of State, GMB launched the Expanded Program on Immunization (EPI). So, I expect the current pace of immunization to be sustained and even improved. I also see the National Health Insurance Scheme (NHIS) being rapidly rolled out to cover every Nigerian. With an improved uptake of the NHIS, healthcare will become more accessible and affordable.

In secondary care, I foresee GMB putting pressure on State Governments to ensure that the General Hospitals in the states are working. In the past, the PTF equipped many General Hospitals in the country. It is therefore easy for me to expect drugs, equipment and personnel to be available in these centers. There will probably be more incentives for doctors to actually live/work in semi-urban and rural areas where many of these general hospitals are located. I believe incentives will work better than coercion or force. The referral link between the primary and secondary care centers will have to be reinforced as well. This will help to reduce the Infant Mortality Rate as well as the Maternal Mortality Rate.

For tertiary centers, I think GMB’s commitment should be to enhance training and retraining of future specialist doctors and other health professionals. Research should be encouraged and incentivized. There is a gross absence of funds for quality and meaningful research in Nigeria. Without research, medical science cannot grow. Without research, we will still rely on medical technology from the Western world and now the Eastern world. With meaningful research on the other hand, our tertiary hospitals will grow and be able to offer specialized services to reduce the current trend of medical tourism.

One of the reasons for medical tourism is the inability of our major centers to diagnose and handle many diseases. GMB will most likely stop government officials from spending the Nation’s foreign exchange on incessant medical trips for ailments that can be conveniently handled in Nigeria. This move will ensure that these monies are plowed back into our health system and help improve performance.

Hmm, what will happen in the pharmaceutical sub-sector? Going by his love for Nigerian products, GMB will probably encourage our pharmaceutical companies to develop drugs using local raw materials and indigenous technology. In addition, I can still remember seeing the PTF branded drug envelopes containing good quality generic drugs as a medical student in the 90s. So, I envisage the availability of standard drugs in our hospitals. The influx of fake drugs across our borders will be stopped or at least reduced. The National Agency for Food and Drug Administration and Control (NAFDAC) will also be empowered to actually control the administration of food and drugs.

For private hospitals, I expect improved regulations and monitoring (not harassment) from government agencies. The aim should be to standardize practice and boost quality. I expect a closer partnership between government and the private sector in healthcare delivery. Though he was not really open to foreign investment in his ‘first coming’, I expect GMB to partner with local and foreign investors to build and operate world class specialist facilities in all the geopolitical zones of the country.

GMB should also work towards fostering unity and teamwork in the health sector. At present, teamwork in the nation’s hospitals is at an all time low. This problem is not related to Nigeria alone. Recently, I read an article highlighting a relationship issue between anesthetic nurses and physician anesthesiologists in the US. 

Though this problem seems to be universal, I think it can be reduced when there is mutual respect, less egoism and less grandstanding among healthcare professionals. There should be a consistent and conscious realization that everyone has a place in the medical team. Health professionals should remember that though the sky is large enough for every star to shine and be noticed, having two captains on one ship could lead to disaster. The patient should be the focus of healthcare delivery and not individual units of the health team.

If the way the Lagos State government has handled striking doctors is anything to go by, and if GMB’s reaction to the strike led by Professor Ransome-Kuti in 1984 is taken into consideration, then a GMB presidency may not be receptive to incessant strike actions in the health sector. Alternative dispute resolution mechanisms should therefore be sought after. Mediation and Arbitration should be actively encouraged and outcomes respected by all concerned. Using strong arm tactics may be counter-productive in the long run. It may only encourage another mass exodus of doctors that we badly need to meet APC’s target of 50 physicians/1000 Nigerians.

Before I end this post, I am quite sure that GMB will tackle the endemic corruption in the health sector. This will make certain that the money for healthcare will actually be spent on health; not on private mansions.

On a final note, I eagerly look forward to a positive change in Nigeria’s health sector. If actions do speak louder than words, then the health sector will do extremely well under a GMB Presidency.


Congratulations to all Nigerians on a peaceful and successful election. Cheers!

Monday, 2 March 2015

SUPERBUGS Vs. Superman?: The 9 ‘ifs’ that may help


The film Superman premiered in Hollywood in 1978. I watched it in Nigeria in the early 80s and loved it. I was intrigued by the handsome well-built caped man who came from Krypton and could fly at supersonic speed. He could single handedly deal with Villains from all over Space. His arch enemy was the Villain Lex Luther whom he fought and captured at the end of the film. Though in normal life he was a clumsy newspaper reporter called Clark Kent, Superman was the defender of Planet Earth. He performed his super hero duties responsibly despite developing a romantic relationship with a beautiful female colleague, Lois Lane. I have always enjoyed watching Super heroes reigning supreme over Villains.

That is why I wonder why there is no Medical Superman to handle the Villain Superbugs ravaging our medical world today. Why are we constantly been defeated by tiny microscopic Superbugs? What is a Superbug anyway? Superbug is the layman’s terminology for multi-drug resistant bacteria. These are bacteria that are resistant to many forms of standard antibiotics and cause infections that are difficult to treat.

Superbugs have been well documented in Europe, North America and India. It was shown that Superbugs caused an estimated 5000 deaths in the UK in 2012. In the US, they are linked to 2 million cases of illnesses per annum, cause 23,000 deaths and account for healthcare costs of $20billion annually. Methicillin Resistant Staphylococcus Aureus MRSA (shown below) is an example of a superbug.

However, the most recent Superbug in the Medical world is the Carbapeneum Resistant Enterobacteriaceae (CRE). CRE is responsible for the latest superbug attack in America; 7 patients were infected with this superbug, 2 of which are dead and about 179 others are estimated to have been exposed to the bacteria. These patients are believed to have been infected between October 2014 and January 2015 in a UCLA hospital where they underwent endoscopy for the investigation of pancreatic and biliary duct disease. A special duodenoscope manufactured by Olympus Corp. called Q180V was used. The company has since been sued by relatives of infected patients. Though the Food and Drug Administration (FDA) recently approved a superman drug developed jointly by Actavic PLc and AstraZeneca called Avycaz (ceftazidime and avibactam) to combat Superbugs, there are still justifiable fears that this may not be enough.


 What makes this Superbug attack so unique is that these procedures were said to have been done under strict aseptic conditions. The scopes were properly sterilized after each procedure according to manufacturer’s instructions. Patients were not expected to get infected, yet they did. That means the superbugs were able to break through our last line of defense-sterilization of equipment. We seem to be at their mercy now. This much was stated by an infectious disease expert from Duke University, Dr Derrick Anderson when he said there were “no breaks in the disinfection process yet infection arose”. He concluded that there was “no solution presently” to superbugs. Sounds like Lex Luther just gave Superman a sucker punch!

Superbugs get their awesome powers of antibiotic resistance in two ways. First, resistance can be formed from vertical genetic variation through random mutation. Secondly, (and Superbugs love this route of acquiring resistance) resistance is acquired through horizontal transfer of plasmids. These plasmids contain DNA coded against specific antibiotics. When they get into the new bacteria, they are incorporated into the chromosome of the new bacteria. Many of these plasmids contain DNA against different kinds of antibiotics. The end result is the production and proliferation of multi drug resistant bacteria- the Superbugs.

Superbugs seem to be getting the upper hand against the Medical Superman basically because of improper antibiotic use and poor infection control in healthcare facilities worldwide. For instance, doctors have been known to transmit another superbug, Clostridium difficle Infection (CDI) from one patient to another through their unwashed hands. In this case, a simple hand wash with soap and water will help to prevent CDI. 

In the case of the CRE, a simple redesign of the endoscope making it easier to clean properly may be the solution. It may also not be out of place for manufacturers to consider single-use disposable parts when designing scopes.

However, the big question is how do we get Superman to destroy these villains once and for all time? How do we preserve our health and those of future generations? How do we carry out even the most minor surgical procedure without the fear of superbugs hindering recovery? How do we ensure that antibiotics continue to handle bacterial infections successfully?

The solution may lie in implementing the 9 ‘ifs’:
  • ·        If patients do not request for drugs every time they visit a Physician
  • ·        If patients comply with dosage instructions when they are given antibiotics
  • ·        If Physicians do not prescribe antibiotics excessively (one study showed that 30-50% of antibiotic use was inappropriate)
  • ·        If there are stricter and enforceable controls for antibiotic use in all nations of the world
  • ·        If hospitals comply with infection control techniques 100% of the time
  • ·        If the use of sub-optimal dosage of antibiotics in livestock farming is stopped
  • ·        If pharmaceutical companies can better control the antibiotic waste water effluents they regularly discharge into the environment
  • ·        If pharmaceutical companies will fund more research into discovering newer antibiotics
  • ·        If we can develop and promote alternatives to antibiotic therapy e.g. stool transplant, probiotics, cytokines etc


Until we can implement these measures, the Superbugs may continue giving our Medical Superman a torrid time.


Monday, 23 February 2015

THE MEASLES IMMUNIZATION DEBACLE IN THE US AND THE AFRICAN PERSPECTIVE II


The Commentaries
Some commentators have said that the US have gotten too used to medical success and forgotten what measles really is. Many of the modern day parents were vaccinated against the disease as infants and have never seen a case of measles or experienced its severe complications. Even the prominent advocates of freedom of choice in America were vaccinated for measles as kids. Since they don’t know what the disease is, they can afford to prevent their kids from getting their shots. After all, a man cannot run when he neither feels nor thinks something is chasing him. I do agree with the notion that Americans are getting complacent with basic public health issues like vaccination.


In Africa, we can barely afford such complacency. The horrors of poorly treated and untreated measles are evident among us. We still see deaths from measles. Vaccination rates in Nigeria for instance are between 50-79%, 80-89% for Ghana and less than 50% for South Sudan. So we cannot be accused of complacency. Our problem may well be illiteracy and ignorance among parents who refuse vaccination for their children. I long for the day when Africa can afford to sit back and see measles conquered and driven out of the continent like the former colonial masters were.



Another reason for American parents refusing vaccination may be their lack of trust for medical science in general and the big pharmaceutical companies in particular. Some Americans now feel that medical science cannot be trusted; that doctors always hide information from their patients; that medicine causes more harm than good; that the measles vaccine causes more deaths than measles itself. Informed commentators like Dawn Babcock Pabble have pointed out that the disease caused only 450 deaths per year in the USA before the introduction of the vaccine. Such people may be missing the point by looking at the death statistics alone. It goes beyond death. Anti-vaccination campaigners seem to forget about the cases of deafness, blindness and mental retardation caused by measles. They also seem to forget the amount of money used to treat measles patients, the uncertainties and emotional trauma their parents experience and the inevitable fear of death hanging over these children. In addition, they forget the people who are already immuno-compromised or who have leukemia. Such patients cannot take any vaccine and depend on the immunity of others to survive. They are therefore at risk of dying if others do not get vaccinated.


 The anti-vaccination guys also point out that these vaccines are manufactured by large pharmaceutical giants who rake in huge profits annually. Could this be the reason why they continually push more vaccines to the public so that their owners can get wealthier? Some may posit that probably, there are no inherent benefits in these vaccines. Though such suspicions are understandable, it amounts to paranoia when there are no hard facts to support them. While it may be true that the vaccine makers make more money than they should, should we stop using their products that have been scientifically proven to save lives? The Americans and indeed the whole world may be suffering from “informational gluttony” or information overload.

This leads to the issue of unhindered public access to junk science as well as access to compromised studies like the Wakefield study. In the past, medical science was limited to doctors and people in the medical community. Now, anyone can simply go to the internet and “whip” up 20 causes of anemia in less than a minute. While this trend may be considered beneficial to all concerned, caution must be applied. The internet has not only made correct information accessible but has also put a lot of incorrect facts out there. People will generally believe what they choose to believe and when a lie is repeatedly told, it begins to sound like the truth. This may be a major reason why American parents are beginning to believe that vaccines are dangerous and should be avoided. They are ignorant of the scientific fact that the incidence of measles in America is still relatively low because of the herd immunity they currently enjoy. This herd immunity is derived from the large number of people that are already immunized. However, when more and more kids refuse immunization, this herd immunity will be gradually eroded. Then the Americans may find themselves back in the pre-1963 era. That is the danger that they are subjecting themselves and the rest of the world to.

(If this were an African country, the major news stations in the West will be shouting themselves hoarse about how primitive Africans are by now. I still remember how Nigeria kept on appearing on the map of “Ebola countries” in one international news station even after the country had been declared Ebola free by the World Health Organization (WHO). I hope no one will accuse me of reverse discrimination. I simply cannot afford the cost of litigation.)

Talking about cost, the ballooning cost of healthcare in the USA has also not helped the pro-vaccination cause. With healthcare getting more expensive, and health insurance companies struggling to stay afloat, it will not come as a surprise that Americans are thinking of cutting down their medical bills. A major contributor to this health costs may be the several tests conducted and treatments given to patients that are simply not needed. More access to medical knowledge has made doctors prescribe more and more drugs to avoid future litigations. This has pushed the health cost higher and higher. Though vaccination is covered by standard health insurance, many Americans feel that the current immunization schedule is not set up in an optimal cost effective way. One American parent complained of his child getting 23 vaccination shots in just one year compared to the 8 shots he had in the 80s when growing up! Are ALL of these vaccines necessary or are Americans just simply been extravagant because they have “excess” medical knowledge? It is unlikely that an African parent will subject his/her child to such torture in the name of preventing diseases. So, if a parent disagrees with this schedule, he/she may be excused.

The real solution though may be to reduce the current vaccination regimen to acceptable levels. Isn’t it possible to remove some of the inoculations? The notion that one size fits all may actually be a dangerous one and may be the cause of the adverse reactions that is often talked about. The future of safer measles vaccination may lie in the ability of medical science to make vaccinations individualized through the use of genetics and molecular biology.

The Politicians

Funny as it may sound, some opposition politicians have latched onto the vaccination saga to score cheap political points. It is shocking that even first world politicians will stoop so low as to use just about anything to discredit the Obama administration. While I cannot give judgment on his health policies, I erroneously thought that only African politicians play such mischievous “politricks”. New Jersey Governor Chris Christie and Kentucky Senator Rand Paul both stand out in this hall of shame. Governor Chris Christie initially stated publicly that parents should have "some measure of choice" in vaccinating their children and Senator Rand Paul called the decision not to vaccinate "an issue of freedom.

" Freedom!!!??? When a person’s freedom endangers the life of other people’s children it ceases to be freedom. It becomes an assault! If people have the freedom not to vaccinate their children, then drunk drivers should be allowed on the roads and smokers allowed to smoke on commercial flights. The remarks of these two gentlemen have stoked the controversy further and given impetus to the anti-vaccination movement.

 Here in Africa, it has also been reported that highly influential figures deny their children vaccination as well. This accounts for the presence of polio in Nigeria till date. Americans should be wary of such politicians as Christie and Rand who seem to want to take them back to the dark ages by their statements. They should probably watch out for them in 2016 when they launch their respective presidential campaigns.

Risks, Benefits and the Middle Ground

It must be realized at this point that there are risks as well as benefits to the measles vaccination. A proper risk-benefit analysis should be conducted to determine the full extent of this.  In highlighting the risks of vaccination, it is important to recall that the association between measles vaccine and autism has been scientifically disproved several times. That leaves the incidence of adverse reactions like febrile convulsions and thrombocytopenia purpura. Since these are relatively rare, isn’t it wiser to still give the vaccine and prevent blindness, deafness, mental retardation and death?

The anti-vaccination camp will wisely remind us all that the “rare” cases of febrile seizures and thrombocytopenia purpura are not just cases. Rather, they are children born to loving parents, with siblings and other caring relatives. Should they become sacrificial lambs for the good of society? In the same vein, the pro-vaccination camp will probably retort “is it better to endanger the entire population and spend millions of dollars to treat and rehabilitate measles patients because an infinitesimal few will get thrombocytopenia purpura?”

 The middle ground here will be to ask “how committed is the medical community to making vaccines safer for the populace?” If vaccines are made safer, then there will be less adverse effects or no adverse effects. Then the anti-vaccination guys will probably be convinced to allow their children get vaccinated. Then this whole debate will end and Americans will begin to behave like the responsible people they are known to be. Then I can stop writing this article and go to sleep.

If wishes were horses, beggars they say will ride. The debate will probably go on forever because vaccines may never be 100% safe. No drug can ever be 100% free of side effects. (Though, I still recall one of my lecturers in medical school saying “never use the word ‘never’ in medicine”). But as Africans, we must draw some lessons from the measles debacle in America.


Firstly, we should strive to eradicate measles by encouraging vaccination. Maybe then, we can begin to consider opting out of vaccination. Next, politics should never be allowed to come between proven medical science and the lives of our citizens. We should also educate our populace by regularly giving out correct and factual health information. Next, we should remember that good Patient care does not necessarily mean doing more tests and prescribing more medication but rather optimizing available resources to achieve good health. Finally, we should never take success for granted and become complacent like the Americans seem to be doing.

I rest my case. Thanks for reading this rather long post. See you again......

Tuesday, 17 February 2015

THE MEASLES IMMUNIZATION DEBACLE IN THE US AND THE AFRICAN PERSPECTIVE


Since the beginning of the year, the medical world has being awash with news of the latest measles outbreak in America. Many were shocked to hear that some American parents were refusing to get their children vaccinated against measles. Not very often do we hear news of such major failings in the Western world. That a major superpower has an outbreak of measles in contemporary times is unimaginable. Imagine an African tribesman in a remote African village without access to space technology launching a spacecraft to Mars! Or a neonate that can speak perfect Chinese at birth! It is that strange. Before judgment is passed on such a highly informed people, it is only fair to first examine the origin of this latest story.

The Official Story
The Centers for Disease Control and Prevention (CDC) claims that the “outbreak likely started from a traveler who became infected overseas with measles then visited an amusement park in California while infectious”. Since then, about 121 people across 17 states and Washington DC have been reported to have measles. 85% (103) have been linked to the initial case in December 2014. The CDC rushed to contain the outbreak and counseled vaccination to prevent a reoccurrence. Some politicians with (? African DNA) then decided to play “politricks” with the issue and shouted that parents had a right to prevent their children from being vaccinated! 


Hence, the debate started with the pro-vaccination guys trying to shout down the anti-vaccination guys; and the anti-vaccination guys shouting right back at them. What a titanic battle it has been since then with the different camps quoting scientific studies to support their claims. Last week, some parents were rumored to have organized so called “measles parties” in California. These parties are said to be willingly organized gatherings between healthy children and measles-infected children so that the non-infected and healthy children can get infected with the virus and acquire immunity. They prefer to give children the disease rather than the vaccine! This raises the question of how dangerous is this disease and how safe is the vaccine?

The Disease
Measles is considered one of the most contagious viral diseases on earth. A patient with measles can directly infect between 12-18 people while a patient with mumps can directly infect 4-7. A patient with measles can also infect a non-immune person up to 2hrs after the infected person has left a room. That is how contagious it is. It is also quite fatal. The World Health Organization (WHO) considers measles as one of the leading causes of death among children worldwide. In 2013 145,700 children died from measles alone. It also leads to disabilities like mental retardation, deafness and blindness. It causes complications like diarrhea, dehydration, pneumonia and encephalitis. It causes a rare but long term complication called Subacute Sclerosing Pan Encephalitis or SSPE. These are all well documented. There is presently no approved specific antiviral treatment for measles. So, one wonders why a loving parent will refuse to have his/her child vaccinated to protect the child from such harm. The answer may lie at the flipside of the coin; the measles vaccine.

The Vaccine




The measles vaccine is a live attenuated vaccine usually given before the 1st birthday and between 6-8years. (The exact time of vaccination varies across countries). The vaccine can be given as a standalone injection or in combination with others e.g. the Measles, Mumps and Rubella vaccine or MMR. The measles vaccine was developed by Dr. John Franklin Enders who worked with Dr. Thomas C. Peebles at Children's Hospital Boston. According to Wikipedia, the first clinical trials of the measles vaccine were undertaken by David Morley at the Wesley Guild Hospital in Ilesha, Nigeria on his own children. The vaccine was then introduced to the US in 1963 and has since helped to reduce the incidence of measles from hundreds of thousands pre-1963 to barely less than 200 cases in 1997-2013. In fact the CDC declared measles eradicated from America in 2000. This feat was achieved through an excellent vaccination program that spanned four decades. But in 2014 there was a rise to 610 cases and 121 cases have been reported in January- February 2015 alone.
Before the worldwide drive for immunization began in 1980, measles caused approximately 2.6 million deaths annually. From 2000-2013, measles vaccination prevented about 15.6 million deaths. The vaccine though potent has certain drawbacks as well. The reported drawbacks of the vaccine are fever, injection site pain and, in rare cases, Thrombocytopenic purpura. There have also been reported cases of febrile seizures after vaccination. Serious side effects are extremely rare.

The Controversy

The present measles vaccination controversy was probably started in 1998, when a British gastroenterologist Andrew Wakefield published a study in The Lancet medical journal linking measles with autism. The study was later proved to be false and withdrawn by the reputable Journal in 2010. Dr Wakefield then had his medical license withdrawn because he was found to have received money ($675,000) from a lawyer who was suing the vaccine makers. Yet another study by Dr. Lee Hieb, an orthopaedic surgeon and past president of the Association of American Physicians and Surgeons stoked the Controversy fire even more. Her study showed that since 2005 there have been 86 deaths from the MMR vaccine – 68 of them children under the age of 3 years old. In addition the anti-vaccination guys have shouted to high heavens that the CDC has reported no case of death from measles in the last 12 years as against 108 cases of adverse reaction to the vaccine reported in the same period.


The burden of evidence though, seems to lie in favor of no association between measles and autism in particular. According to USA TODAY, fourteen scientific studies have found no link between measles vaccines and autism. Seven have found no link between autism and thimerosal, a preservative no longer used in childhood vaccines. And two studies have failed to find any link between autism and the number of vaccines a child gets. Several respected Medical bodies have also joined in the debate. The Centers for Disease Control and Prevention, the Institute of Medicine of the National Academy of Sciences, the UK National Health Service and the Cochrane Library review have all concluded that there is no evidence of a link between the MMR vaccine and autism.


How did the USA which previously hailed vaccination as a scientific miracle now come to regard it as a negative phenomenon? Why after several years of successfully fighting the virus will they say that their weapons are now dangerous?

Watch out for answers in my next post.